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Premise: In return for joining Orochimaru's forces and lending them her, er, unique healing powers and willingness to experiment on unwilling participants, Karin had to be offered something, right? Well, in this drabble universe, she was offered a way to be biologically female. That's right, Karin will be MtF. To do this, Orochimaru developed a jutsu that changed her on a cellular level, and we'll say it works something like viruses would work in the Naruto universe, since it has only a passing acquaintance with reality anyway. This virus was not meant to move beyond Karin--obviously, because then Orochimaru wouldn't have let Sasuke chew on her--but something went wrong, and the dormant virus jutsu became active in Sasuke, making him patient 0. The symptoms took several weeks to manifest, and by that time, he had returned to Konoha. Oops.
Contagious through chakra, the genderswitching quickly became epidemic among ninjas. While some people have different degrees of natural immunity, most ninja are vulnerable to it. As of the time of drabbling, there is no cure, though methods of containment are being exercised.
omg girlsuke. girlitachi. potential for sakusasu reverse-het and nejihina yuri. *__*
... Anyway. The post is here:
http://sarolynne.livejournal.com/191780.html